| 1–5 | Power for a Shadowed ProbeRadioisotope power for a probe in long darkness: fission vs combustion, alpha decay, cross-linked insulation, Group 13Nuclear chemistry · Materials and structure · Periodic patterns · Engineering design (HS-PS1-8, HS-PS2-6, HS-PS1-1, HS-ETS1-1) | 3 MC, 2 CR | Practice cluster |
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| 6–10 | Glass for Repeated HeatingBorosilicate beakers heated and rinsed: B vs Al trends, network covalent bonding, evaporation of three liquids, polarityPeriodic patterns · Bonding and formulas · Materials and structure · Intermolecular forces · Polarity and molecular structure (HS-PS1-1, HS-PS1-2, HS-PS2-6, HS-PS1-3, HS-PS3-5) | 3 MC, 2 CR | Practice cluster |
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| 11–15 | Air Under PressureStored air in a syringe and a heated rigid bottle: Boyle's law, pressure vs temperature, O₂ in air at STP, specific heatGases · Stoichiometry and conservation · Thermochemistry (HS-PS1-9, HS-PS1-7, HS-PS3-1) | 3 MC, 2 CR | Practice cluster |
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| 21–25 | Acidity in a Yogurt ModelMilk with yogurt starter vs a control: pH and hydronium ions, Brønsted–Lowry acids, indicator ranges, boiling pointAcids and bases · Solutions (HS-PS1-11, HS-PS1-10) | 3 MC, 2 CR | Practice cluster |
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| 26–30 | A Stain and a CatalystProtease in laundry: activation energy from a potential energy table, temperature and rate, O₂ at STP, specific heatThermochemistry · Reaction rates · Stoichiometry and conservation (HS-PS1-4, HS-PS1-5, HS-PS1-7, HS-PS3-1) | 3 MC, 2 CR | Practice cluster |
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| 31–35 | Refining an Ammonia ProcessHaber–Bosch design trade-offs: pressure and Le Châtelier's principle, Group 15 bond energy trends, NH₃ mass, catalystsPeriodic patterns · Stoichiometry and conservation · Equilibrium · Engineering design · Reaction rates (HS-PS1-1, HS-PS1-7, HS-PS1-6, HS-ETS1-3, HS-PS1-5) | 3 MC, 2 CR | Practice cluster |
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| 36–40 | A Rechargeable Spacecraft BatteryHubble's nickel–hydrogen cells on discharge: half-reactions, oxidation numbers, metallic bonding, and water near Ni²⁺Oxidation and reduction · Materials and structure · Polarity and molecular structure (HS-PS1-12, HS-PS2-6, HS-PS3-5) | 3 MC, 2 CR | Practice cluster |
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| 41–45 | Air Passing a Wet SurfaceEvaporative cooler pads: surface polarity, vapor pressure, heat of vaporization, percent by mass, and water around ionsIntermolecular forces · Thermochemistry · Solutions · Polarity and molecular structure (HS-PS1-3, HS-PS3-1, HS-PS1-10, HS-PS3-5) | 3 MC, 2 CR | Practice cluster |
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| 46–50 | Light for an Orbital GardenSpace-garden lights without UV: photon energy by color, a glowing indicator's electrons, leaf reflectance, photosynthesisElectromagnetic radiation · Photosynthesis · Engineering design (HS-PS4-4, HS-LS1-5, HS-ETS1-2) | 3 MC, 2 CR | Practice cluster |
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